Sparks, Dr. James

Distinguished Professor of Health Sciences
School of Arts and Sciences
PhD in Biology and Biochemistry, University of Tennessee
BS in Zoology and Chemistry, University of Tennessee


Dr. Sparks is a Distinguished Professor of Health Sciences at Carolina University.  He is retired from the Corporate Vice Presidency for Innovation post at Franciscan Alliance, Mishawaka, IN, and was previously the first President and CEO of the Franciscan central clinical laboratory, Alverno Clinical Labs.  In his role as Corporate VP, Innovation, he led corporate patient safety, care quality, clinical technology assessment  and best practices performance improvement in support of all 14 hospitals.

His background includes leadership positions in both hospital (University of Tennessee Memorial Research Center and Hospital, Knoxville, TN) and commercial laboratory entities, including Regional Director of laboratories for SmithKline Bio-Science Laboratories (St. Louis, MO and Los Angeles, CA) and Nichols Institute (El Paso TX and San Juan Capistrano, CA) both of which are now part of Quest Laboratories.  He was also Chief Operations Officer and Site Director for Genetic Design, an identity/paternity laboratory based in Greensboro, NC, for which he led the sales process to LabCorp in Burlington, NC.   He is the author or co-author of 28 published scientific articles.

In addition to his current teaching roles, Dr. Sparks is an active healthcare consultant, assisting Franciscan Alliance, Inc, the 14-hospital system for which he worked full-time until 2015, as leader of the clinical Technology Assessment Committee and as innovation consultant.


Susie, D., J.C. Sparks, and D. Kentera
The renin-angiotensin systems in rats with hereditary hydronephrosis, Circulation, Supplement IV to Vols. VII and Vlll :IV-30, 1973. (Abst.)

Susie, D., J.C. Sparks, B.B. Lozzio, and D. Kentera
Effect of diuretics on the renin-angiotensin system in unilaterally nephrectomized rats. Clinical Research 22 (1):13A, 1974. (Abst.)

Susie, D., J.C. Sparks, B.B. Lozzio, and D. Kentera
Evidence that nephrotensin (Grollman) is involved in the development of renal hypertension. Clinical Research 22 (1):13A , 1974. (Abst.)

Susie D., and J.C. Sparks
The renin-angiotensin system of uninephrectomizedrats under diuretics treatment. Res. Comm. Chem.Pathol. Pharm. 8:423-429 , 1974.

Susie, D., and J.C. Sparks
Aspirin induced volume expansion in salt loaded rats. IRCS Med. Sci. 2:1424, 1974.

Susie, D. and J.C. Sparks
Salt-induced hypertension in rats with hereditary hydronephrosis. Circulation, Supplement Ill to Vols. 49 and 50:111-32 , 1974 . (Abst.)

Susie, D. and J.C. Sparks
Hydronephrosis , hypertension and plasma renin activity. NEJM 290:909, 1974. (Letter)

Eubanks, AL., J.C. Sparks and M.R. Pelton
Selected chemical analyses of black bear serum.
J. Tenn. Acad. Sci. 51:29-31, 1975.

Sparks, J.C. and D. Susie
Rapid onset of salt-induced hypertension in rats with hereditary hydronephrosis.
Res. Comm. Chem. Pathol. Pharm. 11:425-433, 1975.

Susie, D., J.C. Sparks and E.A. Machado
Protective role of the renal medulla in salt-induced hypertension: Effects of salt loading on blood pressure and plasma volume in hydronephrotic rats with renomedullary transplants.
IRCS Med. Sci. 3:84, 1975.

Susie, D. and J.C. Sparks
Differentiation of nephrotensin from the renin-angiotensin system. Proc. Soc. Exp. Biol. Med. 148:957-960, 1975.

Susie, D., J.C. Sparks, D. Kentera and B.B. Lozzio
The renin-angiotensin system in rats with hereditary hydronephrosis. Pfluger's Arch. - Eur. J. Physiol. 358(3):265-274, 1975.

Susie, D. and J.C. Sparks
Physiological actions of renomedullary prostaglandins - a viewpoint. (Invited editorial)
IRCS Med. Sci. 3:363-366, 1975.

Susie, D. and J.C. Sparks
Effects of aspirin on renal sodium excretion, blood pressure and plasma and extracellular fluid volume in salt-loaded rats.
Prostaglandins10(5):825-831, 1975.

Susie, D., J.C. Sparks and E.A. Machado
Renomedullary deficiency - a contributory factor in the pathogenesis of experimental renal hypertension.
Experientia 32:354-355, 1976.

Lange, RD., J.B. Jones, C. Chamber, Y. Quirin and J.C. Sparks
Erythropoiesis and erythrocytic survival in dogs with cyclic hematopoiesis. Amer. J. Vet. Res. 37(3):331-334, 1976.

Susie, D., J.C. Sparks, and E.A. Machado
Salt-induced hypertension in rats with hereditary hydronephrosis: The effect of renomedullary transplantation.
J. Lab. Clin. Med. 87:232-239, 1976.

Susie, D., J.C. Sparks, and E.A. Machado
The effects of renomedullary transplantation on blood pressure, cardiac output and peripheral resistance during the development of one-kidney renal hypertension.
IRCS Med. Sci. 4:47, 1976.

Sparks, J.C. and D. Susie
The effects of propranolol on plasma renin activity and renal renin concentration in rats on normal and sodium-deficient diets.
Pharmacol. Res. Commun. 9:479-487, 1977.

Susie, D., J.C. Sparks and D. Kentera
Suppressed antihypertensive function of the renal medulla in rats with spontaneous hypertension.
Pfluger's Arch. - Eur. J. Physiol. 368:173-175, 1977.

Susie, D., J.C. Sparks, E.A. Machado and D. Kentera
The mechanism of renomedullary antihypertensive action: Hemodynamic studies in hydronephrotic rats with one-kidney, renal-clip hypertension.
Clin. Sci. Mol. Med. 54:361-367, 1978.

Stewart, C., J.C. Sparks, P. Bodlaender and J. Cuan
Control of an assay for thyroxine in blood spots collected on filter paper. Clin. Chem. 24(8):1038, 1978. (Abst.)

Sparks, J.C.
Oestradiol receptor and progesterone receptor assays: Distribution of over 5000 consecutive results.
J. Clin. Chem. Clin. Biochem. 19(8):844, 1981. (Abst.)

Sparks, J.C., A. Vekich, E Abellera and G. Kalchschmid
Radioimmunoassay of thyroglobulin antibodies using Staphylococcus aureus containing protein A. Clin. Chem. 28(7):1597, 1982. (Abst.)

Maxon, H.R., S.R. Thomas, A. Boehringer, J. Drilling , M.I. Sperling, J.C. Sparks and I.W. Chen
Low iodine diet in 1131 ablation of thyroid remnants.
Clin. Nuclear Med. 8(3):123-126, 1983.

Sparks, J.C.
Quality control of endocrine assays: Calibration of peptide hormone radioimmunoassays.
Qual. Assur. News 1(6):51-52, 1983.

Hauser, C.J., R O. Kamrath, J.C. Sparks and W.C. Shoemaker Calcium homeostasis in acute pancreatitis.
Surgery 94(5):830-835, 1983.

Aubrey, W.M., J.C. Sparks and G.D. Braunstein
Evaluation of serum amino- and carboxyterminal parathyroid hormone measurements in hemodialysis patients with and without radiographic renal osteodystrophy.
Mt. Sinai J. Med. 51(2):132-137, 1984.

Sparks, Dr. James